Skip to content
Fullscript leaf logo
Create account
Fullscript logo
Fullscript leaf logo
  • Solutions
    • Plan care
      Lab testing Offer end-to-end diagnostics.
      Supplement catalog Recommend healthcare’s best.
      Clinical decision support Optimize your patients’ plans.
      Evidence-based templates Build complete plans quickly.
    • Deliver care
      Online plans Send individual and multi-patient plans.
      Wholesale ordering Dispense supplements from your clinic.
    • Engage patients
      Patient experience See how patients thrive on Fullscript.
      Adherence & insights Keep patients on track with less effort.
      Patient promotions Offer savings, engage patients in a few clicks.
    • IntegrationsSee all integrations
  • Resources
    • Learn
      How to use Fullscript Explore quick demos, articles, and more.
      Wellness blog Education for practitioners and patients.
      Webinars 100+ recordings of practitioner discussions.
      Protocols Our library of evidence-based protocols.
      Clinical evidence Studies that support the Fullscript platform.
      Practice resources Handouts, promotional tools, and more.
      Ingredient library Decision support for supplement ingredients.
    • Featured
      lets make healthcare whole kyle feature image
      Let’s Make Healthcare Whole

      Learn how Fullscript is making whole person care more attainable, scalable, and impactful.

  • Pricing
Sign in Create account Book a demo Sign in
Supplement Ingredients
—

Top Bone Broth Benefits

Updated on June 27, 2025 | Published on September 26, 2022
Fact checked
Jayelah Bush, BScN Avatar
Written by Jayelah Bush, BScN
Dr. Natacha Montpellier, ND, B.Sc.
Medically reviewed by Dr. Natacha Montpellier, ND, B.Sc.
  1. Wellness blog
  2. Top Bone Broth Benefits

Bone broth (stock) is a liquid made from simmering bones in water over a period of time. Drinking bone broth on its own, or using it as a base for soups and other dishes, is a great way to get its health benefits. Bone broth contains many important nutrients, including amino acids, collagen, and protein. (11) Scientific evidence suggests that the nutrients in bone broth may support digestive health, joint health, a healthy immune system, and more. 

Keep reading below to learn about bone broth benefits, and how to make your own bone broth at home. 

5 bone broth benefits

Amino acids, the building blocks of proteins in our cells and tissues, are one of the main components of bone broth. Proteins are used within the body to perform many bodily functions as well as repair, build, and grow bodily tissues. (7)(15) Research indicates that the components of bone broth can benefit the body from head to toe, from mental health to skin health. 

top 5 bone broth benefits
Learn about the top benefits of bone broth.

1. Brain health 

Bone broth is a good source of the amino acid glycine, which plays a key role as a neurotransmitter (messenger between nerves and cells), influencing brain development, motor skills, and behavior. (4)(11)(18) Glycine also has anti-inflammatory and antioxidant properties.Research demonstrates that glycine can decrease neurological (brain and spinal cord) damage related to oxidative stress in mice. (22) Cellular damage related to oxidative stress can negatively affect the nervous system, potentially playing a role in the development of neurological diseases such as Alzheimer’s disease and Parkinson’s disease. (19)

bone broth benefits hero image
One of the benefits of bone broth is its high amino acid content. (11)

2. Gut health

Beef bone broth is rich in the amino acid glutamine, the most abundant and widely used amino acid in the body. (7)(11) About 30% of total body glutamine is used by the digestive tract to support intestinal health. Its functions include supporting a healthy inflammatory response, maintaining the intestinal barrier, and regulating intestinal cell death. (10) In gut health conditions such as inflammatory bowel disease, glutamine levels are significantly lower than healthy individuals. (8) Regularly drinking bone broth may help increase glutamine levels to support digestive health. (11)

3. Immune health 

Not only is glutamine a key nutrient for a healthy gut but also a healthy immune system. Leukocytes (white blood cells) require glutamine for proper function. During illness or injury, glutamine is used by the immune system just as much, if not more, than glucose (sugar), the main source of energy for the human body. Glutamine can be created within the body, but levels are often insufficient during times of illness. Research indicates that supplementing with glutamine before or after a major health event, such as bone marrow transplantation, radiation treatment, or surgery, may be beneficial for immune health. (7)

4. Joint health

Joint pain related to osteoarthritis (joint damage) is one of the most common causes of chronic pain, affecting millions of North Americans. (6)(17) Osteoarthritis occurs when joint cartilage (tough, flexible tissue) degrades, causing bones to scrape against each other as the joint moves. This can eventually cause pain and negatively impact all areas of connective tissue, including bone, cartilage, ligaments, and tendons. (5)(13) Collagen is the main structural protein found in skin and other connective tissues, such as cartilage. Collagen can be synthesized in the body using amino acids, or obtained from dietary or supplement sources. (23) Consuming more collagen and collagen-building amino acids and nutrients may be one way to promote bone and joint health. (2)(17) 

Bone broth is a good dietary source of collagen and collagen-building amino acids. (11) Clinical and animal research has demonstrated that supplementing with collagen extract derived from chicken bones, like that from chicken bone broth, may be effective for decreasing joint pain. (12)(20) 

woman eating a bowl of bone broth soup
Chicken soup made with bone broth may support joint health and help reduce the negative effects of connective tissue stress, such as chronic pain. (12)

5. Skin health 

Skin, the body’s largest organ, contains up to 70% of collagen, which plays an important role in maintaining skin structure and elasticity. (3)(21) Aging reduces collagen production within the body, which can weaken skin elasticity and strength, causing the skin to become thin, dry, and wrinkled. (3) Research suggests that collagen is a major component in the “anti-aging” of skin. (21) Bone broth collagen may be just what your skin needs for a youthful glow. 

Bone broth precautions 

Bone marrow is the fatty, soft, spongey tissue found in the center of most bones. Marrow bones (e.g., femur) are good choices for bone broth as they contain high amounts of collagen and amino acids. As a fatty tissue, bone marrow is also a rich source of vitamin D, which is stored in fat. One reported case has noted that regularly drinking high volumes of bone broth, notably beef bone broth, may lead to hypervitaminosis D (excess vitamin D). (16) Hypervitaminosis D can lead to hypercalcemia (excess blood calcium) which can cause serious health complications, including fragile bones, fatigue, and vomiting. (14)

In addition to the important amino acids and key nutrients found in animal bones, there may also be trace amounts of heavy metals, such as lead. However, research indicates that the levels of heavy metals present in bone broths are not considered dangerous, falling within the Maximim Residue Limits (MRLs) established by the U.S. Department of Agriculture. (9) 

Homemade bone broth recipe

Making bone broth at home on the stovetop or in a slow cooker is the best way to get its amazing health benefits. A study reported that store-bought bone broth was found to be lower in all amino acids than the self-prepared varieties. (1) While it may sound daunting, making your own bone broth is actually fairly simple.

simple bone broth recipe
Follow these simple steps to create a delicious bone broth.

The bottom line 

The health benefits of bone broth come from its rich nutrient content, including the protein collagen and its related amino acids. Consuming bone broth may support a variety of health facets, including mental health and joint health. Bone broth is mostly considered safe, but may contain trace amounts of heavy metals and can lead to vitamin D toxicity if consumed in excess. Sourcing high-quality animal bones and making bone broth at home is one way to limit toxin exposure and increase the nutrient content. If you’re a patient, consult with your integrative healthcare provider before making any major changes to your diet. 

Simplify the delivery of whole person care

Create free account I'm a patient
References
  1. Alcock, R. D., Shaw, G. C., & Burke, L. M. (2019). Bone broth unlikely to provide reliable concentrations of collagen precursors compared with supplemental sources of collagen used in collagen research. International journal of sport nutrition and exercise metabolism, 29(3), 265–272. 
  2. Alcock, R. D., Shaw, G. C., Tee, N., & Burke, L. M. (2019). Plasma amino acid concentrations after the ingestion of dairy and collagen proteins, in healthy active males. Frontiers in nutrition, 6, 163.
  3. Asserin, J., Lati, E., Shioya, T., & Prawitt, J. (2015). The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: Evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, 14(4), 291–301. 
  4. Avila, A., Nguyen, L., & Rigo, J. M. (2013). Glycine receptors and brain development. Frontiers in Cellular Neuroscience, 7.
  5. Centers for Disease Control and Prevention. (2020). Osteoarthritis (OA). https://www.cdc.gov/arthritis/osteoarthritis/index.html 
  6. Centers for Disease Control and Prevention. (2022). Joint pain and arthritis. https://www.cdc.gov/arthritis/caring/index.html 
  7. Cruzat, V., Macedo Rogero, M., Noel Keane, K., Curi, R., & Newsholme, P. (2018). Glutamine: Metabolism and immune function, supplementation and clinical translation. Nutrients, 10(11), 1564. 
  8. He, F., Wu, C., Li, P., Li, N., Zhang, D., Zhu, Q., Ren, W., & Peng, Y. (2018). Functions and signaling pathways of amino acids in intestinal Inflammation. BioMed research international, 2018, 9171905. 
  9. Hsu, D. J., Lee, C. W., Tsai, W. C., & Chien, Y. C. (2017). Essential and toxic metals in animal bone broths. Food & nutrition research, 61(1), 1347478. 
  10. Kim, M. H., & Kim, H. (2017). The roles of glutamine in the intestine and its implication in intestinal diseases. International journal of molecular sciences, 18(5), 1051. 
  11. Mar-Solís, L. M., Soto-Domínguez, A., Rodríguez-Tovar, L. E., Rodríguez-Rocha, H., García-García, A., Aguirre-Arzola, V. E., Zamora-Ávila, D. E., … & Castillo-Velázquez, U. (2021). Analysis of the anti-inflammatory capacity of bone broth in a murine model of ulcerative colitis. Medicina (Kaunas, Lithuania), 57(11), 1138. 
  12. Mobasheri, A., Mahmoudian, A., Kalvaityte, U., Uzieliene, I., Larder, C. E., Iskandar, M. M., Kubow, S., … & Zuscik, M. J. (2021. A white paper on collagen hydrolyzates and ultrahydrolyzates: Potential supplements to support joint health in osteoarthritis? Current Rheumatology Reports, 23(11).
  13. National Institute of Arthritis and Musculoskeletal and Skin Diseases. (2019). Overview of osteoarthritis. https://www.niams.nih.gov/health-topics/osteoarthritis 
  14. National Institutes of Health . (2020). Hypercalcemia. MedlinePlus. https://medlineplus.gov/ency/article/000365.htm 
  15. National Institutes of Health . (2021). Amino acids. MedlinePlus. https://medlineplus.gov/ency/article/002222.htm 
  16. Pandita, K. K., Pandita, S., & Hassan, T. (2011). “Toxic” beef bone soup. Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases, 8(2), 43–44.
  17. Woo, T., Lau, L., Cheung, N., & Chan, P. (2017). Efficacy of oral collagen in joint pain – osteoarthritis and rheumatoid arthritis. Journal of Arthritis, 06(02).
  18. Razak, M. A., Begum, P. S., Viswanath, B., & Rajagopal, S. (2017). Multifarious beneficial effect of nonessential amino acid, glycine: A review. Oxidative medicine and cellular longevity, 2017, 1716701. 
  19. Salim S. (2017). Oxidative stress and the central nervous system. The Journal of pharmacology and experimental therapeutics, 360(1), 201–205.
  20. Schauss, A. G., Stenehjem, J., Park, J., Endres, J. R., & Clewell, A. (2012). Effect of the novel low molecular weight hydrolyzed chicken sternal cartilage extract, BioCell Collagen, on improving osteoarthritis-related symptoms: A randomized, double-blind, placebo-controlled trial. Journal of agricultural and food chemistry, 60(16), 4096–4101. 
  21. Seol, J. Y., Yoon, J. Y., Jeong, H. S., Joo, N., & Choi, S. Y. (2016). Anti-aging effects of the hanwoo leg bone, foot and tail infusions (HLI, HFI and HTI) on skin fibroblast. Korean journal for food science of animal resources, 36(2), 237–243. 
  22. Ullah, R., Jo, M. H., Riaz, M., Alam, S. I., Saeed, K., Ali, W., Rehman, I. U., … & Kim, M. O. (2020). Glycine, the smallest amino acid, confers neuroprotection against D-galactose-induced neurodegeneration and memory impairment by regulating c-Jun N-terminal kinase in the mouse brain. Journal of neuroinflammation, 17(1), 303. 
  23. Wu, M., Cronin, K., & Crane, J. S. (2021). Biochemistry, collagen synthesis. In StatPearls. StatPearls Publishing.

Author

Jayelah Bush, BScN Avatar
Written by Jayelah Bush, BScN
Dr. Natacha Montpellier, ND, B.Sc.
Medically reviewed by Dr. Natacha Montpellier, ND, B.Sc.

Disclaimer

The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

SHARE THIS POST
  • Print
  • Email
  • Facebook
  • LinkedIn
  • Twitter
  • Pinterest

More resources

Protocols
Practice resources
Ingredient library
Webinars

Make healthcare whole with Fullscript

Join 100,000+ providers building the future of whole person care today.

Create free account

Read more articles

Article
—Accessing Creatine Potency
Creatine supports muscle health and performance, but quality varies. Fullscript’s Quality Program te...
Article
—Assessing Collagen Potency
Collagen supports joints, skin, and tissues, but quality varies. Fullscript’s Quality Program tests...
Article
—Vitamin B3 Potency: A Hidden Variable in Supplementation
Vitamin B3 supports energy and DNA health, but dose inconsistencies pose risks. Fullscript’s Quality...

Fullscript content philosophy

At Fullscript, we are committed to curating accurate, and reliable educational content for providers and patients alike. Our educational offerings cover a broad range of topics related to whole person care, such as supplement ingredients, diet, lifestyle, and health conditions.

Medically reviewed by expert practitioners and our internal Medical Advisory Team, all Fullscript content adheres to the following guidelines:

  1. In order to provide unbiased and transparent education, information is based on a research review and obtained from trustworthy sources, such as peer-reviewed articles and government websites. All medical statements are linked to the original reference and all sources of information are disclosed within the article.
  2. Information about supplements is always based on ingredients. No specific products are mentioned or promoted within educational content.
  3. A strict policy against plagiarism is maintained; all our content is unique, curated by our team of writers and editors at Fullscript. Attribution to individual writers and editors is clearly stated in each article.
  4. Resources for patients are intended to be educational and do not replace the relationship between health practitioners and patients. In all content, we clearly recommend that readers refer back to their healthcare practitioners for all health-related questions.
  5. All content is updated on a regular basis to account for new research and industry trends, and the last update date is listed at the top of every article.
  6. Potential conflicts of interest are clearly disclosed.
Learn more

The healthiest cookies you’ll choose today

Our website uses cookies to collect useful information that lets us and our partners support basic functionality, analyze visitor traffic, deliver a better user experience, and provide ads tailored to your interests. Agreeing to the use of cookies is your choice. Learn more

Fullscript leaf icon
Platform
  • What’s new
  • Integrations
  • Testimonials
  • Catalog
Company
  • About us
  • Blog
  • Why Fullscript
  • Careers
  • Partnerships
  • Quality program
Help
  • Book a demo
  • Support Center
  • Provider FAQs
  • Patient FAQ
  • Contact us
  • Security
Developers
  • Engineering at Fullscript
  • API

© Fullscript 2025. All rights reserved.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

  • Privacy Statement
  • Terms of Service
  • Accessibility Policy
  • Customer Support Policy
  • Acceptable Use Policy
  • Privacy Rights Notice
  • Auto Refill Terms and Conditions
  • Consumer Health Data Privacy Notice
American flag - toggles to show american specific contentUS
Canadian flag - toggles to show canada specific contentCanada