Sisu Protocol

Mental Health

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This protocol was developed for practitioners using Fullscript in Canada and the templates cannot be applied to accounts operating outside of Canada.

Magnesium 250 Relaxation Blend

Take 4.4 grams (1 scoop) once daily or as directed by a health care practitioner. The powder may be dissolved in 250 ml of cold or warm water, or to taste.

Temporarily promotes relaxation, helping to ease some of the negative effects of stress such as irritability or decreased mood, while improving sleep quality. Magnesium 250 Relaxation Blend is gentle, non-sedating, and non-habit forming and also helps reverse the agitating effects of taking excess caffeine.

Features 250 mg of magnesium bisglycinate/citrate per dose for enhanced bioavailability and absorption. Magnesium deficiency is associated with anxiety, confusion, insomnia, and depression. Supplementation has been shown to balance mood, improve sleep quality, and decrease memory loss. Added L-theanine (an amino acid found in green tea) promotes restfulness and alleviates anxiety. It has also been clinically shown to improve overall cognitive function. GABA (gamma aminobutyric acid) has been shown to alleviate the adverse effects of stress such as restlessness and trouble sleeping, while also decreasing the stress caused by mental work.

Magnesium Relaxation Blend is a non-sedating, easy-to-mix powder available in great-tasting raspberry lemonade, tart cherry, and honey grapefruit flavors, lightly sweetened with stevia and non-GMO fructose. The tart cherry and raspberry lemonade flavors are suitable for vegan diets.

B Calm with Rhodiola

Take 2 capsules daily or as directed by a health care practitioner

Full-spectrum B vitamin formula plus rhodiola to balance mood and support overall health, particularly in people under physical or mental stress. Ideal for those following a vegetarian or vegan diet.

B Calm with Rhodiola contains a full range of energy-supporting B vitamins to calm the nervous system and regulate hormone levels. Supplementation with B vitamins has been clinically shown to alleviate stress and improve mood, while deficiencies are associated with memory loss and cognitive impairment. B Calm with Rhodiola also contains rhodiola (Rhodiola rosea), an adaptogen that helps to normalize the production of certain hormones to invigorate a sluggish nervous system or calm an agitated one. Rhodiola has been shown in studies to decrease mental fatigue while improving mental and physical performance. Provides safe and effective stress support, with no jitteriness, drowsiness, or post-supplementation “crash.”

5-HTP 100mg

Take 1 capsule, three times daily or as directed by a health care practitioner

High-potency 5-HTP helps to promote healthy mood balance by increasing serotonin levels and helps to improve sleep.

Provides 100 mg of 5-HTP (from the Griffonia simplicifolia seed) per capsule. 5-HTP is well-absorbed orally and, unlike many substances, is able to cross the blood-brain barrier. Studies show that supplementation with 5-HTP, a naturally occurring amino acid, can raise levels of serotonin (the “happy hormone”), while reducing symptoms associated with low serotonin, including anxiety, depression, and insomnia. It has also been shown to decrease pain and fatigue associated with fibromyalgia, and may aid in weight management by regulating cravings and appetite.

Full Spectrum Omega

Take 3 capsules, one time per day or as directed by a health care practitioner

High-potency wild Alaskan salmon oil in the triglyceride form with 17 naturally occurring fatty acids to support mood, cognitive function, and hormonal health

Sustainably sourced, IFFO-certified, wild Alaskan salmon oil provides a full range of 17 naturally occurring fatty acids, including the essential omegas-3 and omega-6 fatty acids (EFAs). In addition to supporting cardiovascular, immune, skin, and eye health, omega-3 fatty acids may help to balance mood, alleviating both anxiety and depression. By decreasing levels of inflammation-promoting prostaglandins, EFAs have also been shown to promote blood flow to the brain, improving memory and cognitive function, even in young adults. Added vitamin D3 offers additional immune system support, while astaxanthin supplementation has shown the ability to further reduce markers of inflammation as well as potentially slow the cellular aging process.


The Fullscript Integrative Medical Advisory team has developed or collected these protocols from practitioners and supplier partners to help health care practitioners make decisions when building treatment plans. By adding this protocol to your Fullscript template library, you understand and accept that the recommendations in the protocol are for initial guidance and may not be appropriate for every patient.

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