Fullscript Protocols

Respiratory Care

Clinical research suggests that certain supplement ingredients may support respiratory health.

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Protocols Fullscript Protocols
Respiratory Care

Protocol development in integrative medicine is not typically a simple process. Individuals require individualized care, and what works for one patient may not work for another.

As a result, the Fullscript Integrative Medical Advisory team advises using an evidence-informed approach to protocol development. To simplify this process for practitioners, we have assembled a sampling of evidence-based standardized protocols that practitioners can use as a foundation when developing individualized protocols.

To establish these protocols, we first developed a Rating Scale that could be used to discern the rigor of evidence supporting a specific nutrient’s therapeutic effect.

The following protocols were developed using only A through D-quality evidence. These are categorized as follows:

Class Qualifying studies Minimum requirements
A Systematic review or meta-analysis of human trials
B Human RDBPC ≥ 2 studies and/or 1 study with ≥ 50
C Human RDBPC or RCT 1 study < 50 subjects
D Human trials or In-vivo animal trials

RDBPC = Randomized Double-Blind Placebo Controlled
RCT = Randomized Controlled Trials

Please refer to the complete Rating Scale for further information.


The Fullscript Integrative Medical Advisory team has developed or collected these protocols from practitioners and supplier partners to help health care practitioners make decisions when building treatment plans. By adding this protocol to your Fullscript template library, you understand and accept that the recommendations in the protocol are for initial guidance and may not be appropriate for every patient.

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Respiratory Care


200-340mg, total per day of magnesium citrate, minimum 12 weeks2,3

  • Magnesium has shown to improve FEV11,2
  • The simultaneous long-term administration of magnesium citrate and drug (bronchodilator) in asthmatic children has been shown to be beneficial in the management of asthma3
  • Bronchial reactivity induced by methacholine was decreased by magnesium oral supplementation. It was also shown that magnesium provided better management of the symptoms in pediatric patients with moderate asthma4
  • PEFR increased by 5.8% in addition to an improvement in AQLQ and ACQ2
Magnesium citrate in the Fullscript catalog.

Fish oil 

1.8g EPA 1.3g DHA, total per day, minimum 21 days6

  • EPA and DHA alter the 15-LOX pathway and the subsequent metabolic profile7
  • Omega-3 polyunsaturated fatty acids (PUFAs) decreased airway inflammation markers like 9α, 11β-PGF26
  • The introduction of PUFAs reduced the prevalence of child asthma5
Fish Oil in the Fullscript catalog.

Vitamin C

500-1500mg, total per day of ascorbic acid, minimum 2 weeks8,9,10

  • A protective effect was observed in exercise-induced asthma patients9,10
  • An improvement in post-exercise FEV1, LTC4-E4, 9α, 11β-PGF2 and FENO concentrations were observed in addition to an amelioration in asthma symptom scores10
Vitamin C in the Fullscript catalog.


Systematic review or meta-analysis of human trials
Systematic review or meta-analysis of human trials