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Respiratory Care

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Protocols Fullscript Protocols
Respiratory Care

Protocol development in integrative medicine is not typically a simple process. Individuals require individualized care, and what works for one patient may not work for another.

To establish these protocols, we first developed a Rating Scale that could be used to discern the rigor of evidence supporting a specific nutrient’s therapeutic effect.

The following protocols were developed using only A through C-quality evidence.

A
Systematic review or meta-analysis of human trials
B
RDBPC human trials
2+ studies and/or 1 study with 50 + subjects
C
RDBPC human trials
1 study

Magnesium

200-340 mg, total per day of magnesium citrate, minimum 12 weeks2,3

  • Magnesium has shown to improve FEV11,2
  • The simultaneous long-term administration of magnesium citrate and drug (bronchodilator) in asthmatic children has been shown to be beneficial in the management of asthma3
  • Bronchial reactivity induced by methacholine was decreased by magnesium oral supplementation. It was also shown that magnesium provided better management of the symptoms in pediatric patients with moderate asthma4
  • PEFR increased by 5.8% in addition to an improvement in AQLQ and ACQ2
Magnesium citrate in the Fullscript catalog

Fish oil 

1.8 g EPA 1.3 g DHA, total per day, minimum 21 days6

  • EPA and DHA alter the 15-LOX pathway and the subsequent metabolic profile7
  • Omega-3 polyunsaturated fatty acids (PUFAs) decreased airway inflammation markers like 9α, 11β-PGF26
  • The introduction of PUFAs reduced the prevalence of child asthma5
Fish oil in the Fullscript catalog

Vitamin C

500-1500 mg, total per day of ascorbic acid, minimum 2 weeks8,9,10

  • A protective effect was observed in exercise-induced asthma patients9,10
  • An improvement in post-exercise FEV1, LTC4-E4, 9α, 11β-PGF2 and FENO concentrations were observed in addition to an amelioration in asthma symptom scores10
Vitamin C in the Fullscript catalog

Disclaimer

The Fullscript Integrative Medical Advisory team has developed or collected these protocols from practitioners and supplier partners to help health care practitioners make decisions when building treatment plans. By adding this protocol to your Fullscript template library, you understand and accept that the recommendations in the protocol are for initial guidance and may not be appropriate for every patient.

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References

1
Systematic review or meta-analysis of human trials
a
https://www.ncbi.nlm.nih.gov/pubmed/30778086
5
Systematic review or meta-analysis of human trials
a
https://www.ncbi.nlm.nih.gov/pubmed/24265794

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