Intestinal Barrier Function Support
Developed in collaboration with Britta Nevitt, ND
Disclaimer
The Pendulum team has created these protocols in collaboration with practitioners to help healthcare partners make decisions when building treatment plans. When using this protocol, you understand and accept that the recommendations in the protocol are for educational guidance and need to be adapted to meet individual patient needs. This may not be appropriate for every patient.
This protocol is not a substitute for medical advice or intended to diagnose or treat any medical condition.
Description
Akkermansia muciniphila has appeared in over 800 scientific publications, many of which discussed the role of this probiotic in maintaining intestinal integrity. (1)
The primary function of Akkermansia muciniphila is to support healthy mucin layer turnover in the intestines, thus supporting the intestinal lining. This process releases short-chain fatty acids, such as acetate and propionate, that support the abundance and diversity of other health-promoting microorganisms in the gut, including the butyrate-producing strain Clostridium butyricum. Clostridium butyricum is shown to help improve gut barrier function by supporting mucosal layer thickness and tight junction proteins, making it another beneficial strain for the intestinal barrier. (2)
Pendulum supplement plan
- Akkermansia: 1 capsule, once daily with food
- Butyricum: 1 capsule, once daily with food
- Polyphenol Booster: optional add-on to boost Akkermansia, which may further enhance the benefits
Disclaimer
The Fullscript Integrative Medical Advisory team has developed or collected these protocols from practitioners and supplier partners to help health care practitioners make decisions when building treatment plans. By adding this protocol to your Fullscript template library, you understand and accept that the recommendations in the protocol are for initial guidance and may not be appropriate for every patient.
- Geerlings SY, Kostopoulos I, De Vos WM, Belzer C. Microorganisms. 2018; 6(3):75. https://doi.org/10.3390/microorganisms6030075
- Stoeva MK, et al. Gut Microbes. 2021;13(1): e1907272. https://doi.org/10.1080/19490976.2021.1907272
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