The gut-brain axis is a complex, bidirectional communication system between the gastrointestinal tract and the central nervous system. The gut microbiota influences the gut-brain axis. Therefore, changes in the gut microbiota due to factors such as diet and stress may lead to gastrointestinal and psychiatric concerns.
The following is an evidence-based eight-week protocol for supporting the gut-brain axis, the gut microbiota, and mental health.
ZenbiomeTM DUAL contains the novel psychobiotic Bifidobacterium longum 1714™ and the internationally recognized probiotic Bifidobacterium longum 35624™. B. longum 1714™ may help support the cortisol/stress response and promote relaxation and emotional well-being. B. longum 35624™ may help support digestive health and healthy inflammatory levels.*
Some patients may experience some gut changes or discomfort during the first four weeks. This is temporary and an indication that the probiotic cultures are beginning to take effect.
MegaMarine™ is a comprehensive, full-spectrum fish oil formulated to support a healthy gut microbiome. It contains a balanced ratio of EPA, DHA, and the “forgotten” DPA to support healthy immune and gut-barrier function.*
Serum-derived bovine immunoglobulins, found in MegaIgG2000™, may help support a balanced immune system and a healthy gut barrier.*
If patients experience diarrhea, increase by two capsules per day to a dose of 5 g, as tolerated.
MegaSporeBiotic™ is a 100% spore-based probiotic that supports the gut microbiome by promoting microbial diversity and maintaining health-promoting, commensal gut microbes.*
FODMATE is a FODMAP-specific enzymatic blend to support the digestion of fermentable oligosaccharides, disaccharides, and/or monosaccharides.*
Recommend in one- to three-month increments as long-term use will result in decreased microbial diversity.
|Week 1||Week 2||Weeks 3–4||Weeks 5–8|
|Zenbiome™ DUAL||2 capsules per day with a meal|
|MegaMarine™||2 softgels per day with a meal||–|
|Mega IgG2000™||2 capsules twice per day with a meal||–|
|MegaSporeBIotic™||1 capsule every other day||1 capsule per day||2 capsules per day|
|FODMATE™||–||–||–||2 capsules, 2–3 times per day, 15–30 minutes before meals|
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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