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Cardiovascular Health – Blood Pressure Support

Protocols Fullscript Protocols
Cardiovascular Health – Blood Pressure Support

Protocol development in integrative medicine is not typically a simple process. Individuals require individualized care, and what works for one patient may not work for another.
As a result, the Fullscript Integrative Medical Advisory team advises using an evidence-informed approach to protocol development. To simplify this process for practitioners, we have assembled a sampling of evidence-based standardized protocols that practitioners can use as a foundation when developing individualized protocols.
To establish these protocols, we first developed a Rating Scale that could be used to discern the rigor of evidence supporting a specific nutrient’s therapeutic effect.
The following protocols were developed using only A through D-quality evidence. These are categorized as follows:

Class Qualifying studies Minimum requirements
A Systematic review or meta-analysis of human trials
B Human RDBPC ≥ 2 studies and/or 1 study with ≥ 50
subjects
C Human RDBPC or RCT 1 study < 50 subjects
D Human trials or In-vivo animal trials

RDBPC = Randomized Double-Blind Placebo Controlled
RCT = Randomized Controlled Trials

Please refer to the complete Rating Scale for further information.

Disclaimer

The Fullscript Integrative Medical Advisory team has developed or collected these protocols from practitioners and supplier partners to help health care practitioners make decisions when building treatment plans. By adding this protocol to your Fullscript template library, you understand and accept that the recommendations in the protocol are for initial guidance and may not be appropriate for every patient.

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Cardiovascular Health – Blood Pressure Support

Magnesium

300-450mg of elemental magnesium, total per day, 1 to 6 months1,2

  • Consistent supplementation resulted in a decrease of both systolic and diastolic blood pressure1,2
  • An inverse correlation between levels of circulating magnesium and the incidence of hypertension has been clearly identified3,4
Magnesium in the Fullscript catalog.

L-arginine

2.4g, total per day, minimum 6 months5

  • Reduction in blood pressure observed in patients with mild to moderate hypertension5
  • Compared to placebo, L-arginine supplementation was shown to lower systolic blood pressure in patients with gestational hypertension6
L-Arginine in the Fullscript catalog.

Garlic (Allium Sativum)

300 to 960mg, total per day, minimum 8 to 12 weeks7,8,9

  • Consistent supplementation for 8-12 weeks has demonstrated reduction in both systolic and diastolic blood pressure7,8,9,10,11
  • Garlic supplementation is widely considered a safe and effective approach to hypertension7,8,10,11
Garlic (Allium Sativum) in the Fullscript catalog.

References

1
Systematic review or meta-analysis of human trials
a
https://www.ncbi.nlm.nih.gov/pubmed/28724644
2
Systematic review or meta-analysis of human trials
a
https://www.ncbi.nlm.nih.gov/pubmed/27402922
3
Systematic review or meta-analysis of human trials
a
https://www.ncbi.nlm.nih.gov/pubmed/28476161
4
Systematic review or meta-analysis of human trials
a
https://www.ncbi.nlm.nih.gov/pubmed/28927411
6
Systematic review or meta-analysis of human trials
a
https://www.ncbi.nlm.nih.gov/pubmed/23435582
10
Systematic review or meta-analysis of human trials
a
https://www.ncbi.nlm.nih.gov/pubmed/26764326
11
Systematic review or meta-analysis of human trials
a
https://www.ncbi.nlm.nih.gov/pubmed/25837272