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Blood Sugar Support

Protocols Fullscript Protocols
Blood Sugar Support

Protocol development in integrative medicine is not typically a simple process. Individuals require individualized care, and what works for one patient may not work for another.

As a result, the Fullscript Integrative Medical Advisory team advises using an evidence-informed approach to protocol development. To simplify this process for practitioners, we have assembled a sampling of evidence-based standardized protocols that practitioners can use as a foundation when developing individualized protocols.

To establish these protocols, we first developed a Rating Scale that could be used to discern the rigor of evidence supporting a specific nutrient’s therapeutic effect.

The following protocols were developed using only A through D-quality evidence. These are categorized as follows:

Class Qualifying studies Minimum requirements
A Systematic review or meta-analysis of human trials
B Human RDBPC ≥ 2 studies and/or 1 study with ≥ 50
C Human RDBPC or RCT 1 study < 50 subjects
D Human trials or In-vivo animal trials

RDBPC = Randomized Double-Blind Placebo Controlled
RCT = Randomized Controlled Trials

Please refer to the complete Rating Scale for further information.


The Fullscript Integrative Medical Advisory team has developed or collected these protocols from practitioners and supplier partners to help health care practitioners make decisions when building treatment plans. By adding this protocol to your Fullscript template library, you understand and accept that the recommendations in the protocol are for initial guidance and may not be appropriate for every patient.

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Blood Sugar Support


500 mg, three times per day, minimum 12 weeks1

  • In diabetic patients, demonstrated a reduction in blood glucose levels comparable in effect to hypoglycemic pharmaceutical interventions2
  • Overall effectiveness measured by reduction of T2DM biomarkers2
Berberine in the Fullscript catalog.

Chromium Picolinate

500 mcg, two times per day, minimum four weeks3

  • Current literature confirms a minor reduction in blood glucose when supplemented consistently for four weeks or longer3
  • Chromium supplements should be taken with a carbohydrate-containing meal4
Chromium Picolinate in the Fullscript catalog.

Psyllium Husk

5 g, three times per day, minimum six weeks5

  • In diabetic patients, demonstrated minor to moderate reduction in blood glucose levels6
    15 g daily is a minimum dose and can be titrated up gradually to patient tolerance5
  • However, no current literature points to an increased benefit using more than 15 g daily5
Psyllium Husk in the Fullscript catalog.


Systematic review or meta-analysis of human trials