Skip to content
Fullscript Protocol

Aging and Longevity Support

Upload template
Protocols Fullscript Protocols
Aging and Longevity Support

Protocol development in integrative medicine is not typically a simple process. Individuals require individualized care, and what works for one patient may not work for another.

To establish these protocols, we first developed a Rating Scale that could be used to discern the rigor of evidence supporting a specific nutrient’s therapeutic effect.

The following protocols were developed using only B through D-quality evidence.

B
RDBPC human trials
2+ studies and/or 1 study with 50 + subjects
C
RDBPC human trials
1 study
D
Non-RDBPC human or In-vivo animal trials

Multivitamin

Multivitamin formulation, minimum 8 weeks1

  • Multivitamin use was associated with longer telomere length in women aged 35 to 742
  • Multivitamins containing a combination of minerals and herbs were shown to decrease perceived mental stress in an elderly population several hours after intake4
  • Multivitamin intake in elderly women was associated with an increase in inhibitory neural processes, which translates into an improvement in neural efficiency during memory retrieval3
  • Multivitamins were shown to improve alertness and negative mood symptoms in men aged 50 to 69 years old1
Multivitamin in the Fullscript catalog

Omega-3 fatty acids

1.25-2.5 g of Omega-3 PUFA, total per day, minimum 8 weeks5,6,7

  • Omega-3 PUFA has been shown to increase telomerase levels and lengths5,6
  • Omega-3 PUFAs have shown to reduce IL-1β, TNF-α, and IL-6, factors that contribute to the effects of inflammaging7

For a more detailed review of Omega 3 fatty acids, refer to the Fullscript reference sheet: https://fullscript.com/hcp/fish-oil

Omega-3 fatty acids in the Fullscript catalog

New and upcoming research:

Astragalus membracanus

10-50 mg of TA-65, total per day, minimum 12 months8

  • Decline in the percentage of senescent cytotoxic T cells (CD8+ and CD28-) and natural killer cells were observed in seropositive patients9
  • TA-65 has been demonstrated a clinically significant effect in lengthening telomerase and decreasing the percentage of short telomerase8,9
Astragalus membracanus in the Fullscript catalog

Disclaimer

The Fullscript Integrative Medical Advisory team has developed or collected these protocols from practitioners and supplier partners to help health care practitioners make decisions when building treatment plans. By adding this protocol to your Fullscript template library, you understand and accept that the recommendations in the protocol are for initial guidance and may not be appropriate for every patient.

Upload template

Fullscript content philosophy

At Fullscript, we are committed to curating accurate, and reliable educational content for practitioners and patients alike. Our educational offerings cover a broad range of topics related to integrative medicine, such as supplement ingredients, diet, lifestyle, and health conditions.

Medically reviewed by expert practitioners and our internal Integrative Medical Advisory team, all Fullscript content adheres to the following guidelines:

  1. In order to provide unbiased and transparent education, information is based on a research review and obtained from trustworthy sources, such as peer-reviewed articles and government websites. All medical statements are linked to the original reference and all sources of information are disclosed within the article.
  2. Information about supplements is always based on ingredients. No specific products are mentioned or promoted within educational content.
  3. A strict policy against plagiarism is maintained; all our content is unique, curated by our team of writers and editors at Fullscript. Attribution to individual writers and editors is clearly stated in each article.
  4. Resources for patients are intended to be educational and do not replace the relationship between health practitioners and patients. In all content, we clearly recommend that readers refer back to their healthcare practitioners for all health-related questions.
  5. All content is updated on a regular basis to account for new research and industry trends, and the last update date is listed at the top of every article.
  6. Potential conflicts of interest are clearly disclosed.