Astragalus membranaceus, commonly known as astragalus, has been used as a medicinal remedy in Traditional Chinese medicine (TCM) for more than 2,000 years (6) (8) for its antioxidant, anti-inflammatory, immunoregulatory, hepatoprotective, and diuretic effects on human physiology. (6) It may provide benefits for strengthening the immune system, respiratory health, kidney functions, and skin health. Astragalus is also a source of choline, amino acids, calcium, copper, magnesium, and potassium, as well as many other beneficial nutritional compounds. (8) 

Key takeaways: 

• Astragalus may enhance the activity of white blood cells to help support the body fighting infections
• Research suggests astragalus may help improve markers of kidney function, such as eGFR and proteinuria
• Astragalus has a long history of use in reducing the duration and severity of the common cold
• While generally well-tolerated, astragalus may interact with immunosuppressant medications and should be avoided by individuals with autoimmune conditions or those who are pregnant

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What is Astragalus?

Astragalus is a medicinal root valued for its diverse therapeutic effects. It contains several bioactive compounds, including polysaccharides, flavonoids, and saponins. It is also a source of essential nutrients such as amino acids, choline, calcium, magnesium, and potassium. 

Astragalus benefits

Astragalus root can be found in many forms such as teas and powders, tinctures and capsules. This multi-purpose medicinal root may improve immune function, lung health, skin health, and kidney function. (1)(2)(5)(9)(11)(14) 

Astragalus benefits for immune health

More than ever, our immune systems are top of mind. The main job of this system is to protect our bodies against foreign invaders, such as viruses and bacteria we come in contact with in our everyday environments. 

Astragalus’ bioactive components may support our immune system by increasing white blood cell activity, which is essential for preventing and fighting infection and illness caused by viruses and bacteria. (1)(9)(11)

Astragalus benefits for respiratory support

Along with supporting immunity, astragalus may be beneficial for lung health. Used for thousands of years as a remedy for respiratory infection, research has shown that supplementing with extracts of astragalus root may promote healthy respiratory systems. (1) 

Astragalus benefits for skin health

The anti-inflammatory effects of astragalus may be beneficial in addressing inflammatory skin conditions, such as psoriasis. (2)(11) Researchers have investigated the role astragalus has in targeting neutrophils (innate immune cells) to reduce psoriasis-like skin inflammation in mice. The study concluded that the herb may provide anti-inflammatory activity that could position astragalus as a therapeutic remedy for inflammatory skin conditions. (2) However, further human studies are needed to confirm these effects.

The therapeutic properties of astragalus have also been studied in atopic dermatitis, a recurring inflammatory skin condition that involves dysregulation of the skin barrier. One study suggested combining astragalus with the herb Angelica sinensis and concluded that the two together may be even more effective for treating inflammatory skin conditions. The researchers attributed the beneficial effects of the astragalus root to its anti-allergic and anti-inflammatory activity. (3) 

Astragalus benefits for kidney function 

Astragalus is one of the most common herbs used for addressing kidney dysfunction and improving markers of kidney disease. (5)(14) It has been used together with Angelica sinesis for thousands of years in both East Asia and China to treat kidney disease; however, modern science is still investigating the ways in which these herbs protect the kidneys against oxidative stress and kidney disease. (12)  

Kidney function can often be measured by the levels of protein in urine, with higher levels being an indication of poor kidney function. When higher than usual amounts of protein are found in urine, this can be a sign that the kidneys are not functioning as they should, a disorder referred to as proteinuria. (4) Injections of astragalus have been shown to reduce protein makers in the urine as well as other markers of kidney health such as T-lymphocytes levels within three weeks, suggesting regular supplementation of astragalus may be beneficial for those struggling with proteinuria. (4) 

Supplemental astragalus, especially injections should only be used under the supervision of a healthcare practitioner. 

Astragalus side effects 

Astragalus is generally well-tolerated when taken orally at appropriate doses. However, some individuals may experience mild side effects, including:

• Nasal congestion
• Itchy skin or rashes
• Stomach discomfort (8) 

Astragalus safety considerations

It is recommended to avoid astragalus during pregnancy and breastfeeding as there has been little research done on the safety of supplementation during these times. However, a small animal study showed that the consumption of astragalus can be toxic to the mother and fetus. (8)

Given astragalus’ immune regulatory effects, it’s also not recommended that those with autoimmune conditions, such as lupus or multiple sclerosis, supplement with astragalus. (7) Taking astragalus regularly can also negatively affect prescription medications that suppress the immune system. It’s always important to consult with your healthcare practitioner before starting to supplement with astragalus. (8)

Frequently Asked Questions (FAQs) 

Can I take astragalus every day?

For most healthy adults, astragalus is considered safe for daily use at recommended doses. However, it is best to consult with your healthcare provider to determine the duration of use that is right for you.

Is astragalus safe to take with other medications?

Astragalus can interact with medications that suppress the immune system (immunosuppressants) and may affect how the body processes certain drugs. Always provide your healthcare provider with a full list of your medications before starting astragalus.

What is the best way to consume astragalus?

Astragalus is available as a tea, capsule, or liquid tincture. The "best" form depends on your preference and the specific health concern you are addressing. Your provider can recommend a standardized extract to ensure potency and purity.

The bottom line

Used as a remedy in TCM for thousands of years, modern research has confirmed and demonstrated a number of possible benefits of astragalus. (8) Its bioactive components have been studied for their ability to support the immune system, heal respiratory infections, improve kidney disease, and address inflammatory skin conditions such as psoriasis. As with any supplement, consult your healthcare provider to determine the appropriate dosage and ensure it is safe for your specific health needs.

Sleek consumer lab tests offer data, not direction

Influencer-driven lab companies with AI doctors? That’s not how real health functions. Fullscript Journeys gives you the easy lab testing experience you want and a provider to support you when the real work begins.

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