Description
BioDigest provides a comprehensive formula designed to enhance the digestion and absorption of carbohydrates, proteins, lipids, as well as micronutrients. A decline in acid production is associated with a number of conditions, including hypothyroidism and diabetes, along with the normal aging process, and may impair the absorption of a variety of micronutrients (including zinc, iron, vitamin B12) and contribute to bacterial overgrowth in the intestinal tract.1, 2 Hydrochloric acid, complexed to both betaine and glutamic acid, has been shown to normalize gastric pH among participants with impaired acid production, achieving a pH of less than 3 within 10-15 minutes, and duration of over 70 minutes. This effectively improved the absorption of substances dependent upon low gastric pH.3
BioDigest also provides pancreatic enzymes designed to restore normal digestion to those with impaired pancreatic function, with protease, amylase, and lipase activity for digestion of all macronutrients. The inclusion of ox bile promotes not only efficient lipid absorption, but bile acids have recently been shown to enhance the proteolysis of dietary protein as well.4 Additionally, bile acids upregulate brown adipose tissue activity, have antimicrobial activity in the small intestine, and have systemic metabolic and endocrine effects previously unrecognized, influencing thyroid function, metabolism, and glucose and lipid homeostasis.5-8
References:
1. Väkeväinen S, Tillonen J, Salaspuro M, et al. Hypochlorhydria induced by a proton pump inhibitor leads to intragastric microbial production of acetaldehyde from ethanol. Aliment Pharmacol Ther. 2000 Nov;14(11):1511-8.
2. Britton E, McLaughlin JT. Ageing and the gut. Proc Nutr Soc. 2013 Feb;72(1):173-7.
3. Yago MR, Frymoyer A, Benet LZ, et al. The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydria. AAPS J. 2014 Nov;16(6):1358-65. doi: 10.1208/s12248-014-9673-9
4. Gass J, Vora H, Hofmann AF, Gray GM, et al. Enhancement of dietary protein digestion by conjugated bile acids. Gastroenterology. 2007 Jul;133(1):16-23.
5. Broeders EP, Nascimento EB, Havekes B, et al. The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity. Cell Metab. 2015 Sep 1;22(3):418-26.
6. Thomas C, Pellicciari R, Pruzanski M, et al. Targeting bile-acid signalling for metabolic diseases. Nat Rev Drug Discov. 2008 Aug;7(8):678-93.
7. Watanabe M, Houten SM, Mataki C, et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature. 2006 Jan 26;439(7075):484-8. Thomas C, Auwerx J, Schoonjans K. Bile acids and the membrane bile acid receptor TGR5–connecting nutrition and metabolism. Thyroid. 2008 Feb;18(2):167-74.
Take 1 capsule 4 times per day with food, a few hours before or after taking other medications, or as directed by a health care practitioner. Consult a health care practitioner for use beyond 7 days.
Serving Size: 1 Capsule
Amount Per Serving
Betaine HCL ... 240mg
L-Glutamic Acid HCL ... 240mg
Pancreatic Enzymes 11x* ... 70mg
(Sus scrofa)(pancreas)
Protease ... 19, 250 USP
Amylase ... 19, 250 USP
Lipase ... 1, 540 USP
Ox Bile ... 40mg
(Bos taurus)
Pepsin A ... 35mg
(Sus scrofa)(stomach)(350, 000 FCC PU)
Other Ingredients: Gelatin capsule (gelatin, purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant).
This product does not contain
- artificial colors
- artificial preservatives
- artificial sweeteners
- dairy
- sugar
- wheat
- gluten
- yeast
- soy
- egg
- fish
- shellfish
- salt
- tree nuts
- GMOs
Sealed for your protection. Do not use if seal is broken.For freshness, store in a cool, dry place.
Contraindications
Consult a health care practitioner if symptoms persist or worsen. Consult a health care practitioner prior to use if you have faecal impaction or symptoms such as abdominal pain, nausea, vomiting or fever, if you have a peptic ulcer, excess stomach acid, high cholesterol, diabetes, pancreatitis, pancreatic exocrine insufficiency, cystic fibrosis, gastrointestinal lesions/ulcers, if you are taking anticoagulant or anti-inflammatory agents, are having surgery, or are taking thiazide diuretics, corticosteroids, licorice root or other medications or health products which may aggravate electrolyte imbalance. Do not use if you are pregnant or breastfeeding, are sensitive to pancreatic enzymes or pork proteins, have gallstones, bile duct obstruction, abnormal constrictions of the gastrointestinal tract, potential or existing intestinal blockage, a tonic bowel, appendicitis, inflammatory colon disease such as Crohn’s disease or ulcerative colitis, abdominal pain of unknown origin, undiagnosed rectal bleeding, severe dehydration with depleted water or electrolytes, or diarrhoea. Laxative effect may occur. Discontinue use if you experience abdominal pain, cramps, spasms and/or diarrhoea. Hypersensitivity/allergy, nausea, vomiting, abdominal pain/epigastric pain and/or heartburn have been known to occur, in which case discontinue use and consult a health care practitioner. Keep out of reach of children.