Recommending supplements means making decisions with safety in mind — but checking for drug interactions has traditionally meant switching tools or memorizing interactions. Not anymore. Fullscript Assist offers the ability to quickly check for drug-supplement interactions, helping providers spot potential issues instantly — all within the plan-writing experience.
Explore the new Fullscript features by logging in to your Fullscript account
Get startedWhat’s New: Smarter, Safer Recommendations
With Fullscript Assist, you can:
- Check for interactions automatically
See potential interactions between a patient’s reported medications (it will automatically get flagged for you if they’ve uploaded medications using ‘currently taking’ on Fullscript) and supplements while writing a plan. - Level-up your research
Search by medication or supplement ingredient to explore common interactions and risks. - Understand interaction severity and the evidence
Each flagged interaction comes directly from NatMed, and includes a severity rating and a structured evidence grade — with links to the supporting research, so you can assess clinical relevance at a glance or dig deeper as needed. - Write safer public protocols
When building one-to-many templates, avoid ingredients with potentially higher interaction risk - Stay in one workflow
No external databases, no copy-paste. Safety research can happen right in Fullscript.

Why It Matters
Researching supplement-drug interactions can add additional time — but skipping the research or relying exclusively on memory may create risk. This tool helps you make safer protocols faster and easier to write. You stay in control of every decision, but now with greater confidence that you’ve caught possible interactions.
Backed by Trusted Data
Interaction data comes from NatMed, a widely trusted database of integrative research. Every interaction insight links to the evidence and a detailed description — so you can dig deeper and make informed decisions. NatMed updates the data daily, so you’re not referencing outdated info.
The Bottom Line
Fullscript Assist’s drug-interaction feature helps you:
- Confidently assess supplement-medication risks and get auto-generated flags based on a patient’s ‘currently taking’ in Fullscript
- Reduce time spent on external research, allowing you to tap into the trusted NatMed database right inside your plan-writing workflow
- Feel even more confident that supplement recommendations are safe, with an extra gut check more readily available
- Stay in control of every care decision, but with centralized and evidence-based information at your fingertips