3X4 Genetics testing for practitioners: how to order through Fullscript
Licensed practitioners can now order 3X4 Genetics testing directly through Fullscript—integrating pathway-based genetic insights into your existing clinical workflow with no separate account or platform required.

What is 3X4 Genetics?
Rather than reporting isolated markers, 3X4 Genetics groups genetic information by the biological pathways those variants are associated with. The result is a pathway-level view that practitioners can review as part of their own assessment.
Genetic markers associated with biological pathways such as inflammation, methylation, detoxification, hormone and energy balance, bone, collagen and joint health, insulin and glucose balance, cardiovascular health, nutrient demand, and more are reported. Results are structured in a user-friendly manner into easy-to-understand categories for practitioner review.
Tests can be ordered by licensed healthcare practitioners and reviewed as part of their own clinical assessment and individualized care, working alongside patient history and other relevant information.
Quick overview
Founded: 2018
Specialty: Genetic testing with pathway-based reporting
Use case: All health care settings, especially integrative, functional, and precision health
Availability: U.S., South Africa, Japan, UAE, and distributors in UK, Europe and Australia
Support: Provider education and mentorship, interpretation tools, and clinical resources
How 3X4 Genetics tests are used in clinical practice
3X4 Genetics testing can be considered a foundational first step in patient care: a way to provide genetic data organized by pathways that practitioners may review as part of their own care planning. It is not a diagnostic genetic test.
Common clinical contexts include:
- Personalized health and wellness planning
- Nutritional and metabolic considerations
- Cardiovascular health considerations
- Hormone-related patterns
- Biotransformation and oxidative stress pathways
- Multi-system presentations
3X4 Genetics applies a systems-biology framework. It groups genetic variants across biological pathways so practitioners can review the information in an organized format. Rather than interpreting one variant at a time, it organizes genetic variants across 36 biological pathways, which practitioners may review as part of their own assessment.

Laboratory standards and technology
The comprehensive 3X4 Genetics test
The 3X4 Genetics test is pathway-based and focuses on 6 main health categories that cover 36 biological pathways:
Cellular Health – Inflammation, Methylation, Detoxification and Oxidative Stress pathways
Systems – Collagen & joints, Glucose & insulin, Memory & brain health, Bone health, Mood & behavior, Hormone balance, Histamine overload.
Cardiovascular Health – Vascular health, Blood pressure, Blood clotting, Cholesterol
Energy – Pro-inflammatory fat, Adipogenesis, Weight gain & weight loss resistance, Exercise response, Energy expenditure, Appetite & satiety.
Activity – Power, Endurance, Recovery, Injury and Training response
Nutrients – Vitamin B12, Choline, Folate, Salt, Vitamin D, Caffeine, Fatty acids, Gluten, Iron overload, Vitamin C
Frequently ordered 3X4 Genetics tests
3X4 Blueprint™
A DNA-based test that evaluates genetic variants and organizes findings into 36 biological pathways.
Should be used as part of broader individualized clinical assessment and wellness planning.
3X4 Genetics test selection and turnaround times
Turnaround times may vary and are not guaranteed*
Commonly used test | Specimen | Typical turnaround | |
|---|---|---|---|
| Personalized genetic insights | 3X4 Blueprint™ | Cheek swab | ~3–4 weeks |
How 3X4 Genetics tests compare
3X4 Blueprint™ vs. standard genetic reports
3X4 Blueprint™ | Standard genetic testing | |
|---|---|---|
| Focus | Pathway-based analysis and insights | Raw genetic data |
| Output | Structured pathway reports with the use of color and imagery | Varient lists |
| Clinical use | Pathway-organized report for practitioner review | Data reference |
Why order 3X4 Genetics tests through Fullscript
Fullscript allows practitioners to incorporate 3X4 Genetics testing into an existing clinical workflow:
Streamline the lab ordering process within your existing clinical workflow
Send test kits directly to patients or dispense from the clinic
Review results alongside other patient data
Access pricing information prior to ordering
Manage follow-up workflows within a single system
How to order 3X4 Genetics tests
Create a Fullscript account
Add a 3X4 Genetics test to a patient plan and send
Patients receive instructions for payment, shipping, and sample collection
Review results within your Fullscript dashboard
Frequently asked questions about 3X4 Genetics testing
Key takeaways
- 3X4 Genetics provides pathway-based genetic insights
- Tests are designed to evaluate genetic variants across 6 key health areas
- Reports are structured to organize genetic data across 36 biological pathways for practitioner review
- One report covers it. The 3X4 Blueprint gives you the full pathway-level picture, so there's no second genetic test to order.
- Fullscript enables integration of genetic testing into clinical workflows

Start ordering 3X4 Genetics tests
Create a Fullscript account to access 3X4 Genetics testing