Chronic Bowel Inflammation

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Protocols Brand Protocols AOR
Chronic Bowel Inflammation

This protocol was developed for practitioners using Fullscript in Canada and the templates cannot be applied to accounts operating outside of Canada.


The Fullscript Integrative Medical Advisory team has developed or collected these protocols from practitioners and supplier partners to help health care practitioners make decisions when building treatment plans. By adding this protocol to your Fullscript template library, you understand and accept that the recommendations in the protocol are for initial guidance and may not be appropriate for every patient.

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Chronic Bowel Inflammation

Note: Those with IBD are at higher risk for hyperhomocysteinemia due to genetic predispositions (MTHFR).
As with any autoimmune condition, consider a microbial trigger and dysbiosis.

Total Protocol Duration: 12 weeks

IBD Relief or Pro GI Calm

2 capsules, twice per day for 2 weeks before food, week 1 to 12+

Description: A synergistic combo of anti-inflammatory ingredients. Reduces diarrhea.

Curcumin Active or Pro Curcumin

1 capsule, twice per day with food, week 1 to 12+

Acute flare-up: 2 capsules, 2 to 3 times per day for 1 week.

Note: 1 cap (133 mg) = 13 g std curcumin 95%.

Description: Optimized absorption delivering free form curcumin.

Pro GSH Boost

1 capsule, twice per day with food, week 1 to 12+

Description: Increase local intestinal glutathione to reduce oxidative damage to enterocytes.


1 capsule, three times per day with food, week 1 to 12+

Description: Studied combination of probiotics that promote butyrate production, bifidobacterium growth and reduce intestinal pH.

Pro GI Repair

1 scoop, twice per day with food, week 1 to 12+

Description: Anti-inflammatory and promotes the healing of GI lining.

Optional: Methylcobalamin or Pro Methylcobalamin

1 lozenge, once per day, week 1 to 12+

Description: High dose of the active form of B12 to promote production of SAMe, increase energy and replenish nutritional deficiencies.

Optional: Pro Phase II Detox

2 capsules, twice per day with or without food, week 1 to 12+

Description: Helps increase glutathionization (broccoli extract) and upregulates clearance of endotoxins.



The following may be considered according to requirements for additional support.

  • AOR’s Vitamin D to modify Secretory IgA (sIgA) and enhance anti-microbial peptides. Vitamin D is a steroid nuclear regulator important in innate and adaptive immune regulation. Those with IBD have a 2.28 fold increase of vitamin D deficiency.
  • Pro Quercetin or Pro Bioflavonoids to modulate histamine, leukotrienes and COX2 enzyme activity.

Alterations in estrogen signalling have been implicated in the pathogenesis of IBD. Estrogen acts as a nuclear factor, influencing immune-mediated processes and inflammation. For women, consider:

  • Pro Estro Support to decrease beta-glucuronidase to regulate estrogen elimination.
  • Pro Fem Balance as a Selective Estrogen Receptor Modulator (SERM), which modulates ER that have been linked to colonic inflammation and implicated in the pathogenesis of IBD.


AOR Professional not available in retail health-food stores or online to the general public.